Journal: Frontiers in Ecology and Evolution
Article Title: The pygidial gland secretion of Laemostenus punctatus (Coleoptera, Carabidae): a source of natural agents with antimicrobial, anti-adhesive, and anti-invasive activities
doi: 10.3389/fevo.2023.1148309
Figure Lengend Snippet: FIGURE 1 In vitro determination of interactions of selected secretion’s compounds and antibiotics/antimycotics tested in combinations against the resistant E. coli, methicillin-resistant Staphylococcus aureus (MRSA), P. aeruginosa, and C. auris. A, ampicillin; AmphB, amphotericin B; FA, formic acid; G, gentamicin; NYST, nystatin; OA, oleic acid; R, resistant strains; STR, streptomycin. FICI ≤0.5 = synergistic effect, 2 ≥FICI > 0.5 = additive effect, 4 ≥FICI > 2 = indifferent effect, FICI > 4 = antagonistic effect. All Fractional Inhibitory Concentration Index (FICI) values show significant differences (P < 0.05).
Article Snippet: The human pathogens used in this research were: Escherichia coli ATCC 25922, E. coli resistant strain IBRS E003, Pseudomonas aeruginosa ATCC 27853, P. aeruginosa resistant strain IBRS P001 (gram-negative bacteria), Staphylococcus aureus ATCC 11632, methicillin-resistant S. aureus (MRSA) IBRS 011 (clinical isolate) (gram-positive bacteria), Candida albicans ATCC 10231, C. krusei H1/16 (clinical isolate), C. tropicalis ATCC 750, and C. auris CDC B11903 (fungal strains).
Techniques: In Vitro, Concentration Assay